Tardive Dyskinesia and Schizophrenia :: Biology Essays Research Papers

Moving Ahead, Another Movement Disorder For many years schizophrenia was thought to be caused by bad parenting, the so-called "refrigerator mother" was to blame. Today there exists much more information on the disorder and the evidence points to the commonly accepted notion of a chemical imbalance in the brain. Unfortunately, many people still confuse schizophrenia with multiple personality disorder when, in fact, the two are separate. Schizophrenia however, deals more with people who simply don't have a firm grip on reality. In recent years researchers have made significant advances in the field and have come up with many neuroleptic (antipsychotic) medications to treat the disorder. However along with these medical breakthroughs problems have occurred. The most severe side effect is called Tardive Dyskinesia, literally meaning "late movement disorder." (1) Coined in 1964, it is identified by the involvement of numerous "abnormal, involuntary movements of the orofacial area or extremities." . (2) More specifically, it is characterized by rocking, twisting, jerking, toe tapping, lip smacking, blinking, and most commonly an unusual movement of the tongue. . (1) (2)(3). Interestingly enough, these side effects disappear during sleep. (3) Neuroleptic-induced Tardive Dyskinesia occurs in roughly fifteen to twenty percent of people taking neuroleptic drugs for several years, and often exceeds fifty percent when all patients treated with neuroleptic are considered. (1)(4) Tardive Dyskinesia develops in people of all ages and walks of life, but the elderly, especially men, and those who are mute, unable to reason and understand competently, and those who have lost their teeth are more likely to develop the disorder. (5) The cause of Tardive Dyskinesia has not been positively identified, but researchers do know that neuroleptic drugs change the way nerve impulses jump from the pre-synaptic neurons across a synapse to the post-synaptic neurons. (2). Such drugs prevent the neurotransmitter dopamine from reaching the brain, "directly impairing the function of the basal ganglia and the emotion-regulating limbic system and frontal lobes." (6) Drugs such as Haldol, Navane, Thorazine, Mellaril, Stelazine, Clozaril, and Resperisal are believed to cause Tardive Dyskinesia. (6) Resperidal however, seems to cause a less severe from of Tardive Dyskinesia. (6) Currently researchers are exploring the idea that calcium-channel blockers can treat those with neuroleptic-induced Tardive Dyskinesia. Unfortunately, not enough research has been carried out to date. (7). Recent studies have shown, though somewhat ambiguously, that GABA (gamma amino butyric acid, a usually inhibitory neurotransmitter) gives some improvement over the symptoms of Tardive Dyskinesia.

The Roman Empire and Classical Greece

The Roman Empire and Classical Greece were undeniably two of the greatest societies in history. As far as the political and cultural developments of the two civilizations, the Roman Empire's (approximately the first five centuries of the Common Era) form of government contrasted with that of Classical Greece (approximately 500 B. C. E to 300 B. C. E. ), however the two societies shared similar enthusiasm for literature as well as almost identical religious beliefs.An extremely prominent characteristic of Classical Greece was its decentralized form of government. There, the nation was divided into several polises, or city-states. Each polis had its own government system – which could be a monarchy (the most common), a Tyranny, an Oligarchy, or a Democracy (Athens being the world's first). This is very strange compared to the government of Rome. The Roman Empire was centralized and ruled by one solitary man: the Emperor. Although the senate had some influence of the Roman govern ment, the Emperor held absolute power.Centralization and absolute power was necessary in the large Roman Empire because the vast amount of land being controlled was too much for Rome as a republic to handle. This was not the case in Classical Greece, which was much smaller, and could allow its polises to make their own decisions to keep the people happy. For this reason, we see a difference in the styles of governments of the two societies. Despite this difference though, Classical Greece and The Roman Empire still shared love and support of literature. Several great works of literature came from Classical Greece.During the classical era, many genres of western literature became more prominent. This includes lyrical poetry, odes, pastorals, dramatic presentations of comedy and tragedy, histories, philosophical writings, government writings, and more. Many works from this time became classics in our world today. The Romans also had a strong emphasis on literature and they wrote almos t everything of significance down. It was essential for the Romans to keep extensive written government records on order for them to organize their extremely large empire.Literature was able to strive in both the Roman Empire and Classical Greece because of the emphasis both societies had on education. Without this, neither would have the educated authors, poets, and philosophers needed to produce the great literature that they did. Furthermore, Classical Athens and the Roman Empire shared almost identical religious beliefs. For almost every Greek God, there is a corresponding Roman God. For example, for Zeus there is Jupiter, for Aphrodite there is Venus, Poseidon there is Neptune, and for Hades there is Pluto.The list goes on to include more of the major as well as minor gods, although some gods, such as Apollo, have the same name in each religion. In Rome, despite the change of name, the gods play the same role and have indistinguishable powers to their Greek counterparts. The re ason behind this similarity is that when Rome was developing into a strong civilization, leaders saw the accomplishments of the Greece, especially Athens, and decided to adopt their gods in hopes of reaching the same success.To make them their own, they simply changed the names. Unmistakably similar in their belief systems and love of literature, and at the same time clearly diverse in their forms of government, Classical Greece and the Roman Empire were able to share similarities as well as differences in their cultural and political developments that enabled them to become the prominent and strong civilizations that they did.

`` Twilight `` By Stephanie Meyer - 1889 Words

â€Å"Twilight† by Stephanie Meyer has many codes and conventions from the genre that is gothic literature. Like â€Å"The Italian† by Ann Radcliffe there is a sense of anxiety from the monstrous power of unreality, and the characters of both Bella and Ellena do not know what is happening around them. A dark mystery is created throughout the novels, using sinister settings and threatening atmospheres. The idea of the sublime is shown through the descriptions of Ellena and Bella’s surroundings. This put together with the strange characters they encounter, the sensibility within those characters all work together to slowly build their fears and introduces the idea of the paternal protector, Edward and his family for Bella with Vilvaldi and Schedoni†¦show more content†¦Just like â€Å"Twilight,† â€Å"The Italian’ also communicates the anxieties of women the late 18th to early 20th Century, where middle class women’s homes were becomi ng uncomfortably like a castle or a prison, with constraints on their education and social developments. This is shown in the way female characters always end up trapped within gothic text. When Ellena is kidnapped, even though she faints, it is described differently: ‘All consciousness had now forsaken her’ (Radcliffe, 61). Also when she is taken to the house of Spalatro, she faints, but the words in the narrative say that ‘horror chilled all her frame, and her senses forsook her’ (Radcliffe, 211). Ellena is always thrust back into the middle of peril whenever she seems to reach safety. Ellena is able to remain pure yet strong despite what happens to her; she keeps the Marchesa cleverly controlling, while fearful of her husband finding out her plans. This slightly takes away from the stereotypical damsel in distress, making her seem less weaker than usual. She does not tremble with and fear and does not cry at every misfortune very often but she is also, a lways, saved and protected creating the role in simultaneously restricting women and providing them power. The Sublime also contributes to the mystery: obscure sounds, unexplainable events and dark figures distress and create anxieties within the characters. 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